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C. J. Vaske, Benz, S. C., Sanborn, J. Z., Earl, D., Szeto, C., Zhu, J., Haussler, D., and Stuart, J. M., Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM. Bioinformatics 26, i237–i245 (2010), This paper describes an application of approaches from the probabilistic graphical models in the identification of pathways or dependencies deviating from a given norm. CAS PubMed Article, 2010.