KnockoutNetsInvasivenessGenes

Gene/Class Description GO category
cadherin meeting GO:0016339 GO:0046588
cell cycle meeting
cell adhesion meeting
signal transduction meeting
cell check points meeting
transcription factors meeting
growth factors meeting
receptors meeting
regulation of cell proliferation meeting GO:0042127
VEGF-c Induces metastasis via lymphatic system cell motility
β1 integrins melanoma - lead the way for invasiveness
e cadherin melanoma - cohort of invasive cells bind together with this
leukocyte specific genes these cells regularly invade/extravasate in their normal duty chemotaxis
thrombin/other proteases necessary for extravasation
mesenchymal genes invasive genes resemble these
EMT epithelial-mesenchymal transition (EMT)
gastrulation embryonic EMT
neural crest EMT neural plate -> neural crest
somitogenesis EMT
Palate formation EMT
Mullerian duct regression EMT
Vimentin filament in mesencymal cell cytoskeleton
fibronectin ECM protein